Biotin Anti-Mouse CD154 (MR1)
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The MR1 antibody is specific for mouse CD154, a 39 kD glycoprotein that is primarily expressed on activated T cells. CD154 (CD40 ligand, gp39) binds to CD40 expressed on antigen presenting cells and mediates important costimulatory functions between ≥ ≥ ≥ these cells. Signals generated via cognate interactions between ≥ ≥ ≥ CD154-CD40 on activated T and B cells are required for T-dependent B cell responses. The MR1 antibody is reported to block interaction of CD154 with CD40.
|Name||Biotin Anti-Mouse CD154 (MR1)|
|Alternative Names||CD40L, TRAP, Ly-62, TNF-αSF5|
|Isotype||Armenian Hamster IgG|