The antibody BP53-12 recognizes a defined epitope (aa 16-25) on human p53, a 50 kDa intracellular tumour suppressor found in increased amounts in a wide variety of transformed cells; it is frequently mutated or inactivated in many types of cancer.

PRODUCT DETAILS

Clone: BP53-12

Specificity: P53

Reactivity: Human, Non-Human Primate

Format: Biotin

Isotype: Mouse IgG2a

Application: IHC-P, ICC, FC, ELISA, IP

Storage: 2-8°C protected from light.Do not freeze

Formulation: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Data Sheets: TDS | SDS

RECOMMENDED USAGE

Flow cytometry: Recommended dilution: 1-5 μg/ml. Intracellular staining.

REFERENCES

1. Agarwal ML, et al. 1995. Proc Natl Acad Sci U S A 92:8493-7.
2. Agarwal ML, et al. 1998. Proc Natl Acad Sci U S A 95:14775-80.
3. Taylor WR, et al. 1999. Mol Biol Cell 10:3607-22.
4. Taylor WR, et al. 1999. Oncogene 18:283-95.
5. Tanigawa S, et al. 2008. Biosci Biotechnol Biochem 72:797-804.
6. Bártek J, et al. 1991. Oncogene 6:1699-703.
7. Bártková J, et al. 1991. Int J Cancer 49:196-202.
8. Rössner P Jr, et al. 2002. Mutat Res 517:239-50.
9. Dolezalová H, et al. 1997. Folia Biol (Praha) 43:49-51.

For research use only. Not intended for use in diagnostic procedures.