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Human peripheral blood lymphocytes were stained with 0.5 ug Biotin Anti-Human CD45RA (30-0458) (solid line) or 0.5 ug Biotin Mouse IgG2b isotype control (dashed line), followed by Streptavidin PE.

Biotin Anti-Human CD45RA (HI100)

SKU 30-0458-U025
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The HI100 antibody reacts with the human CD45 isoform known as CD45RA, a protein tyrosine phosphatase of ≥ 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns. With their broad cell distribution, CD45 isoforms are critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RB, CD45RO and others.

The HI100 antibody is widely used as a marker for human CD45RA expression on naive and activated T cells, B cells, and monocytes.

Name Biotin Anti-Human CD45RA (HI100)
Cat. No. 30-0458
Gene ID 5788
Clone HI100
Isotype Mouse IgG2b, kappa
Reactivity Human
Cross Reactivity Chimpanzee
Format Biotin
Application Flow Cytometry
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