Apoptotic and/or necrotic cells display phosphatidylserine (PS) on their outer cell surface, where it acts as an ‘eat-me’ signal and contributes to efficient removal of dead cells by macrophages and other phagocytes. PS is normally only found on the intracellular leaflet of the plasma membrane in healthy cells, but during early apoptosis, membrane asymmetry is lost and PS translocates to the external leaflet. Apotracker™ monomer binds to PS for the detection and removal of dead or dying cells which are effective and preferably at the same time buffer-independent (Calcium free buffer) in comparison to the agents used in the market thus far.

PRODUCT DETAILS

Clone: None

Antibody Type: None

Reactivity: Human, Mouse

Format: Alexa Fluor 647

Host:

Isotype: None

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.