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C57Bl/6 splenocytes were stained with 0.5 ug APC-Cyanine7 Anti-Mouse MHC Class II (25-5321) (solid line) or 0.5 ug APC-Cyanine7 Rat IgG2b isotype control (dashed line).

APC-Cyanine7 Anti-Mouse MHC Class II (I-A/I-E) (M5/114.15.2)

SKU 25-5321-U025
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$83.00

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Description

TDS | SDS

The M5/114.15.2 antibody reacts with mouse MHC Class II alloantigens I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek, as well as being cross-reactive with mouse cells of H-2p and H-2r haplotype. MHC Class II is widely expressed by mouse immune cells bearing these alloantigens, including T and B cells, monocytes, macrophages, and dendritic cells. The antibody does not react with the following alloantigens: I-Af, I-Ak, I-As, or NOD H-2g7.

The M5/114.15.2 antibody may be used for analysis of mouse cells expressing MHC Class II alloantigens as described. Please note that the M5/114.15.2 clone may also be referred to as M5/114 in the literature.

 

Recent Citations:

Burbach BJ, O'Flanagan SD, Shao Q, et al. Irreversible electroporation augments checkpoint immunotherapy in prostate cancer and promotes tumor antigen-specific tissue-resident memory CD8+ T cells. Nat Commun. 2021 Jun 23;12(1):3862. doi: 10.1038/s41467-021-24132-6. PMID: 34162858.

» View on NatureCommunications

Name APC-Cyanine7 Anti-Mouse MHC Class II (I-A/I-E) (M5/114.15.2)
Cat. No. 25-5321
Alternative Names MHC II, IA, IE, I-A/E, IA/IE
Gene ID 14961/14969
Clone M5/114.15.2
Isotype Rat IgG2b, κ
Reactivity Mouse
Format APC-Cyanine7
Application Flow Cytometry
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