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C57Bl/6 splenocytes were stained with 0.5 ug APC-Cy7 Anti-Mouse CD45.2 (25-0454) (solid line) or 0.5 ug APC-Cy7 Mouse IgG2a isotype control (dashed line).

APC-Cyanine7 Anti-Mouse CD45.2 (104)

SKU 25-0454-U025
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The 104 antibody reacts with mouse CD45.2, also known as Ly5.2, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors.

The 104 antibody is typically used as a leukocyte marker in Ly5.2 mouse strains C57BL/6, BALB/c, C58, DBA/1, DBA/2, C3H/He, CBA, 129, A and AKR. The antibody has been demonstrated to be specific for CD45.2 and is not cross-reactive with CD45.1-bearing cells.

Recent Publications:
Martinez-Lopez M, Iborra S, Conde-Garrosa R and Sancho D. 2014. Eur J Immunol. doi: 10.1002/eji.201444651. (Flow Cytometry)

Lin CC, Bradstreet TR, Schwarzkopf EA, Jarjour NN, Chou C, Archambault AS, Sim J, Zinselmeyer BH, Carrero JA, Wu GF, Taneja R, Artyomov MN, Russell JH and Edelson BT. 2016. J Exp Med. 213(2): 251-271. (Flow Cytometry)

Name APC-Cyanine7 Anti-Mouse CD45.2 (104)
Cat. No. 25-0454
Alternative Names Ly5.2
Gene ID 19264
Clone 104
Isotype Mouse IgG2a, κ
Reactivity Mouse
Format APC-Cyanine7
Application Flow Cytometry
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