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Human peripheral blood lymphocytes were stained with 5 uL (0.25 ug) APC-Cy7 Anti-Human CD45 (25-0459) (solid line) or 0.25 ug APC-Cy7 Mouse IgG1 isotype control (dashed line).

APC-Cyanine7 Anti-Human CD45 (HI30)

SKU 25-0459-T025
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The HI30 antibody reacts with human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others.

The HI30 antibody is widely used as a marker for human CD45 expression on T cells, B cells, monocytes, macrophages, and NK cells.

Name APC-Cyanine7 Anti-Human CD45 (HI30)
Cat. No. 25-0459
Alternative Names Leukocyte Common Antigen, LCA, Ly-5
Gene ID 5788
Clone HI30
Isotype Mouse IgG1, kappa
Reactivity Human
Cross Reactivity Chimpanzee
Format APC-Cyanine7
Application Flow Cytometry
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