Vγ3⁺ T cells are the predominant γδ TCR-bearing cells in early fetal thymus. The majority of CD3⁺ cells in 14-day fetal thymus express Vγ3. Vγ3 is also expressed on Thy-1⁺ dendritic epidermal cells (Thy-1⁺ DECs). Cells that express Vγ3 are not significantly detectable in adult lymphoid organs. It has been reported that Lck and Fyn, two Src family kinases, are required for the development of Vγ3⁺ T cells.

Clone 536 reacts with the Vγ3 segment as designated by the Garman nomenclature system. Mouse TCR Vγ3 is also known as TCR Vγ5 under the Heilig & Tonegawa nomenclature system.

Several TCR γ and δ chain nomenclature systems exist. In order to consolidate the various nomenclature systems, we have created charts for corresponding names across some of the most popular naming methods. Click here to see charts.
 

PRODUCT DETAILS

Clone: 536

Antibody Type: Monoclonal

Reactivity: Mouse

Format: APC

Host: Syrian Hamster

Isotype: IgG

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.