APC Anti-Mouse Ly-6G/Ly-6C (Gr-1) (RB6-8C5)
The RB6-8C5 antibody binds to mouse Ly-6G/Ly-6C, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expressed at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils.
Oda Y, Takahashi C, Harada S, Nakamura S, Sun D, Kiso K, Urata Y, Miyachi H, Fujiyoshi Y, Honigmann A, Uchida S, Ishihama Y, Toyoshima F. Discovery of anti-inflammatory physiological peptides that promote tissue repair by reinforcing epithelial barrier formation. Sci Adv. 2021 Nov 19;7(47):eabj6895. doi: 10.1126/sciadv.abj6895. Epub 2021 Nov 17. PMID: 34788088.
Velasco-de Andrés M, Català C, Casadó-Llombart S, et al. The lymphocytic scavenger receptor CD5 shows therapeutic potential in mouse models of fungal infection. Antimicrob Agents Chemother. 2020 Oct 12:AAC.01103-20. doi: 10.1128/AAC.01103-20. PMID: 33046489.
|Name||APC Anti-Mouse Ly-6G (Gr-1) (RB6-8C5)|
|Alternative Names||Gr1, Ly6G|
|Isotype||Rat IgG2b, κ|