APC Anti-Mouse LPAM-1 (DATK32)
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The DATK32 antibody is specific for a combinatorial epitope of the mouse integrin αalpha 4/beta 7 (LPAM-1) heterodimer. LPAM-1 is expressed on most mature lymphocytes and sub-populations of thymocytes and bone marrow cells. It is involved in lymphocyte adhesion and migration and is a receptor for several extracellular matrix proteins including VCAM-1, fibronectin, and MAdCAM-1.
DATK32 is reported to induce LPAM-1 dependent lymphocyte aggregation and block adhesion to VCAM-1, fibronectin, and MAdCAM-1.
|Name||APC Anti-Mouse LPAM-1 (DATK32)|
|Isotype||Mouse IgG2a, κ|