APC Anti-Mouse CD45.1 (A20)
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Description
The A20 antibody reacts with mouse CD45.1, also known as Ly5.1, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors.
The A20 antibody is typically used as a leukocyte marker in Ly5.1 mouse strains: SJL/J, DA, STS/A and RIII. The antibody has been demonstrated to specific for CD45.1 and is not cross-reactive with CD45.2 bearing cells.
Recent Publications:
Miro-Mur F, Perez-de Puig I, Ferrer-Ferrer M, Urra X, Justicia C, Chamorro A and Planas AM. 2015. Brain Behav Immun. doi: 10.1016/j.bbi.2015.08.010. (Flow Cytometry)
| Name | APC Anti-Mouse CD45.1 (A20) |
|---|---|
| Cat. No. | 20-0453 |
| Alternative Names | SJL, Ly5.1 |
| Gene ID | 19264 |
| Clone | A20 |
| Isotype | Mouse IgG2a, κ |
| Reactivity | Mouse |
| Format | APC |
| Application | Flow Cytometry |