CD226 (DNAM-1) is constitutively expressed on native CD8⁺ cells and on CD4⁺ T cells, macrophages and NK cells.This antibody (10E5) was reported to bind about 40% of inactivated CD4⁺ cells and binds only to differentiated Th1 cells, but not to Th2 or Th0 cells.It is also reported to suppress antigen-specific T cell expansion and EAE (experimental allergic encephalitis) mediated by Th1 cells.

PRODUCT DETAILS

Clone: 10E5

Antibody Type: Monoclonal

Reactivity: Mouse

Format: APC

Host: Rat

Isotype: IgG2b, κ

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

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