APC Anti-Mouse CD134 (OX40) (OX-86)
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The OX-86 monoclonal antibody reacts with mouse CD134, a 50kD type 1 integral membrane glycoprotein and a member of the TNF-α receptor superfamily. CD134 is also known as OX40 and is expressed on activated CD4 and CD8 T cells. CD134 is the receptor for CD252 (OX40 ligand) and the interaction of this receptor-ligand pair is implicated in T-dependent humoral responses as well as numerous aspects of T cell expansion, survival and memory. Additionally, CD134 seems to play a significant role in the pathogenesis of some autoimmune diseases.
|Name||APC Anti-Mouse CD134 (OX40) (OX-86)|
|Alternative Names||TNFRSF4, ACT35, OX-40|
|Isotype||Rat IgG1, kappa|