The aryl hydrocarbon receptor (AhR) is a basic helix-loop-helix transcription factor that is activated by multiple ligands such as TCDD. It is expressed in many immune cells and performs an important role in immune regulation. AhR is induced under Th17-polarizing conditions. In its inactive state, AhR is present in the cytoplasm, but upon ligand binding, it translocates to the nucleus. Activation of AhR is tightly controlled by ubiquitination, ligand metabolism, and AhR complex disruption.

PRODUCT DETAILS

Clone: W16012C

Antibody Type: Monoclonal

Reactivity: Mouse

Format: AhR

Host: Rat

Isotype: IgG2b, κ

Applications: ICFC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.