EMR3 is a member of the EGF-7 transmembrane (TM7) adhesion GPCR family. It is predominantly expressed on granulocytes, neutrophils, monocytes, and macrophages, and at lower levels on mature myeloid cells and dendritic cells. EMR3 is absent on lymphocytes, hematopoietic stem cells and myeloid progenitors.

Studies suggest that the EMR3 molecule is upregulated during late stages of neutrophil differentiation and is a marker for terminally differentiated cells. EMR3 may play a role in myeloid-myeloid interactions during immune and inflammatory responses.

PRODUCT DETAILS

Clone: QA20A59

Antibody Type: Recombinant

Reactivity: Human

Format: APC

Host: Mouse

Isotype: IgG1, κ

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.