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Human peripheral blood lymphocytes were stained with 5 uL (0.25 ug) APC Anti-Human CD49d (20-0499) (solid line) or 0.25 ug APC Mouse IgG1 isotype control (dashed line).

APC Anti-Human CD49d (Integrin alpha 4) (9F10)

SKU 20-0499-T025
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The 9F10 monoclonal antibody reacts with human CD49d, a 150kD integral membrane protein that is also known as integrin αalpha4 (ITGA4). Together with integrin αbeta1 (CD29), CD49d forms the VLA-4 heterodimer that serves as a receptor for fibronectin and VCAM-1. VLA-4 is widely expressed on lymphocytes, monocytes, thymocytes, and NK cells. CD49d can also dimerize with integrin αbeta7 to form a receptor that binds the mucosal vascular addressin molecule, MAdCAM-1. CD49d is involved in cellular adhesion to other cells as well as extracellular matrix.

Name APC Anti-Human CD49d (integrin αalpha 4) (9F10)
Cat. No. 20-0499
Alternative Names VLA-4 ? chain, ?4 integrin α, integrin α?4 chain, ITGA4
Clone 9F10
Isotype Mouse IgG1, kappa
Reactivity Human
Format APC
Application Flow Cytometry
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