The mouse monoclonal antibody TS2/7 recognizes an extracellular epitope of CD49a, the alpha 1 chain of VLA integrin complex, that serves as an adhesion receptor for collagen IV and laminin 1.

PRODUCT DETAILS

Clone: TS2/7

Specificity: CD49a

Reactivity: Human, Non-Human Primate

Format: APC

Isotype: Mouse IgG1

Tested Dilution: 5 µL/Test

Application: FC

Storage: 2-8°C protected from light.Do not freeze

Formulation: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Data Sheets: TDS | SDS

RECOMMENDED USAGE

Flow cytometry: The suggested use of this reagent is 5 µL per 1 million cells in a staining volume of 100 µL. If whole blood is analyzed, then use 5 µL per 100 µL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application. The content of a vial (0.5 mL) is sufficient for 100 tests.

REFERENCES

1. Melssen MM, et al. 2018. Oncoimmunology 7:e1490855.
2. Luque A, et al. 1996. J Biol Chem 271:11067-75.
3. Canfield SM, et al. 1999. J Immunol 163:3430-40.
4. Martrus G, et al. 2017. PLoS One 12:e0182532.
5. Thomson-Luque R, et al. 2018. Blood Cells Mol Dis 72:22-33.
6. Marquardt N, et al. 2019. Nat Commun 10:3841.
7. Quardokus EM, et al. 2023. Nat Methods 20:1174-1178.
8. Hemler ME, et al. 1985. J Biol Chem 260:15246-52.

For research use only. Not intended for use in diagnostic procedures.