APC Anti-Human CD23 (EBVCS-5)
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The EBVCS-5 antibody is specific for human CD23, also known as the low affinity IgE receptor (FceRII), a 45 kDa type II transmembrane protein and member of the immunoglobulin superfamily. It is expressed on most B cells and is upregulated upon activation. It is also present on mantle zone B cells, eosinophils, monocytes and a subset of T cells and platelets. CD23 plays a role in B cell development and differentiation, and also functions to regulate IgE production. Soluble secreted forms of CD23 have been reported to bind IgE, stimulate release of pro-inflammatory cytokines from monocytes, and play a role in B cell differentiation.
|Name||APC Anti-Human CD23 (EBVCS-5)|
|Alternative Names||FcER2, Fc?RII, Low affinity immunoglobulin epsilon Fc receptor, BLAST-2, Leu-20, B6|
|Isotype||Mouse IgG1, kappa|