Shopping Cart
Alexa Fluor® 647 anti-TIF1β (KAP-1, TRIM28)

Alexa Fluor® 647 anti-TIF1β (KAP-1, TRIM28)

SKU 619308
Regular price

$361.00

task_alt Added to cart.
View Cart or Continue shopping.
Description

TIFβ (transcription intermediary factor 1-beta) is an 88 kD member of the tripartite motif family. This protein contains three zinc binding domains, a RING domain, a B-box type 1 and type 2 domain, and a coiled-coil region. TIFβ is found in the nucleus and associates with specific chromatin regions. This protein forms a complex with KRAB-domain transcription factors and recruits SETDB1 to histone 3 to increase KRAB-mediated transcriptional repression. TIF1β has been reported to interact with SETDB1 and CBX3 proteins. Studies using knockout mice reveal the important function of TIF1β in regulating genomic imprinting, T cell activation, and T cell tolerance.


PRODUCT DETAILS

Clone: 20A1

Antibody Type: Monoclonal

Reactivity: Human, Mouse

Format: Alexa Fluor 647

Host: Mouse

Isotype: IgG1, κ

Applications: ICC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS



Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.

Shipping
Price calculated at checkout.