Mouse CD68, also known as macrosialin, is an 85-115 kD member of the lysosomal-associated membrane protein (LAMP) family. It is a heavily glycosylated and predominantly intracellular protein, mainly in late endosomes. Macrosialin is the murine homolog to the human macrophage glycoprotein CD68. It is expressed on tissue macrophages, Langerhans cells and at low levels on dendritic cells. High levels of CD68 expression are detected in activated microglia. LAMP proteins may have functions related to cell-cell interaction or cell-ligand interaction. The biological function of CD68 is not completely understood.

PRODUCT DETAILS

Clone: KP1

Antibody Type: Monoclonal

Reactivity: Human

Format: CD68

Host: Mouse

Isotype: IgG1, κ

Applications: IHC-P - Quality tested ICC - Verified

Regulatory Status: RUO

Data Sheets: TDS | SDS

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