The antibody IVA30 reacts with an extracellular epitope on CD41/CD61 complex (bovine), one of the earliest markers of the megakaryocytic lineage. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor, vitronectin, thrombin and mediates platelets aggregation. CD41/CD61 is expressed only by platelets and megakaryocytes; the complex may be absent or strongly reduced in Glanzmann's thrombasthenia (GT). This antibody crossreacts with human platelets.

PRODUCT DETAILS

Clone: IVA30

Specificity: CD41/CD61

Reactivity: Bovine, Human

Format: Purified

Isotype: Mouse IgG2

Application: FC, IP, ICC, ELISA

Storage: 2-8°C protected from light.Do not freeze

Formulation: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Data Sheets: TDS | SDS

RECOMMENDED USAGE

Flow cytometry: Recommended dilution: 1-4 μg/ml.

REFERENCES

1. Mateo A, et al. 1996. Vet Immunol Immunopathol 52:251-3.
2. Naessens J, et al. 1997. Immunol Today 18:365-8.
3. Mateo A, et al. 1996. Vet Immunol Immunopathol 52:363-70.
4. Unknown 1996. Vet Immunol Immunopathol 52:213-468.
5. Simon M, et al. 1996. Vet Immunol Immunopathol 52:377-82.

For research use only. Not intended for use in diagnostic procedures.