The mouse monoclonal antibody MPO421-8B2 recognizes human myeloperoxidase, a heme protein present in intracellular granules of myeloblasts, neutrophils and monocytes. It is a marker of acute myelogenous leukemias and acute lymphoblastic leukemias.

PRODUCT DETAILS

Clone: MPO421-8B2

Specificity: MPO

Reactivity: Human

Format: PE-Cyanine7

Isotype: Mouse IgG1

Tested Dilution: 5 µL/Test

Application: FC

Storage: 2-8°C protected from light.Do not freeze

Formulation: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Data Sheets: TDS | SDS

RECOMMENDED USAGE

Flow cytometry: The suggested use of this reagent is 5 µL per 1 million cells in a staining volume of 100 µL. If whole blood is analyzed, then use 5 µL per 100 µL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application. The content of a vial (0.5 mL) is sufficient for 100 tests.

REFERENCES

1. Ximenes VF, et al. 2009. Biochem J 425:285-93.
2. Hansson M, et al. 2006. Arch Biochem Biophys 445:214-24.
3. Ximenes VF, et al. 2005. J Biol Chem 280:38160-9.
4. Chooklin S, et al. 2009. Hepatobiliary Pancreat Dis Int 8:627-31.
5. Murphy EJ, et al. 2010. Biochemistry 49:2150-8.
6. Locke M, et al. 2020. Sci Rep 10:11694.

For research use only. Not intended for use in diagnostic procedures.

PE-Cyanine7 is a tandem dye made with PE. Caution – Tandem dyes may show changes in their emission spectra with prolonged exposure to light or fixatives.