violetFluor™ 500 Anti-Human CD45 (HI30)
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説明
The HI30 antibody reacts with human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others.
The HI30 antibody is widely used as a marker for human CD45 expression on T cells, B cells, monocytes, macrophages, and NK cells.
Name | violetFluor™ 500 Anti-Human CD45 (HI30) | |
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Cat. No. | 85-0459 | |
Alternative Names | Leukocyte Common Antigen, LCA, Ly-5 | |
Gene ID | 5788 | |
Clone | HI30 | |
Isotype | Mouse IgG1, kappa | |
Reactivity | Human | |
Cross Reactivity | Chimpanzee | |
Format | violetFluor™ 500 | |
Application |
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