violetFluor™ 450 Anti-Human CD19 (HIB19)
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説明
The HIB19 antibody reacts with human CD19, a 95 kDa glycoprotein which acts as a co-receptor, along with CD21, CD81 and CD225, in support of the functional B cell receptor (BCR). This complex provides antigen-specific recognition and subsequent activation of B cells to proliferate and differentiate into antibody-secreting cells (plasma cells) or memory B cells, which are crucial for secondary antigen encounter. CD19 is a lineage-differentiation marker, as its expression is detectable at the earliest B cell stages, through development, and is finally lost upon transition to mature plasma cells.
The HIB19 antibody is widely used as a phenotypic marker for CD19 expression on B cells, as well as on dendritic cell subsets.
Name | violetFluor™ 450 Anti-Human CD19 (HIB19) |
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Cat. No. | 75-0199 |
Alternative Names | Leu-12, B4 |
Gene ID | 930 |
Clone | HIB19 |
Isotype | Mouse IgG1, kappa |
Reactivity | Human |
Format | violetFluor™ 450 |
Application | Flow Cytometry |