The bacterial toxin aerolysin has the remarkable ability to bind selectively and with high affinity to the glycophosphatidylinositol (GPI) anchors of cell surface proteins, causing lysis of normal but not GPI-deficient cells. FLAER is a fluorescently-labeled, inactive variant of aerolysin that does not cause lysis of cells. The reagent binds selectively to cell surface GPI-anchored proteins, but will not bind to cells that are missing GPI-anchors, such as cells with deficiency in any of the phosphatidylinositol glycan complementation groups (PIG) genes.

PRODUCT DETAILS

Clone: None

Antibody Type: None

Reactivity: Human

Format: Spark Blue 488

Host:

Isotype: None

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.