The mouse monoclonal antibody clone dG9 binds to human perforin, a 70 kDa pore-forming cytolytic protein found in the granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. Perforin plays a key role in targeted cell lysis by polymerizing to form a channel in the target cell membrane, which allows cytotoxic proteases like granzyme B to enter the cell.

PRODUCT DETAILS

Clone: dG9

Specificity: Perforin

Reactivity: Human

Format: Purified

Isotype: Mouse IgG2b

Application: IP, IHC-P, ICC, FC-IC

Storage: 2-8°C protected from light.Do not freeze

Formulation: Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

Data Sheets: TDS | SDS

RECOMMENDED USAGE

Flow cytometry: Recommended dilution: 3-12 μg/ml. Intracellular staining.

For research use only. Not intended for use in diagnostic procedures.