The antibody MEM-267 specifically binds extracellularly to the empty but not peptide-loaded form of HLA-DR1. DR is the isotypes of human MHC Class II molecules expressed on antigen-presenting cells (APC; dendritic cells, B lymphocytes, monocytes, macrophages).

PRODUCT DETAILS

Clone: MEM-267

Specificity: MHC Class II (HLA-DR1 (empty))

Reactivity: Human

Format: Purified

Isotype: Mouse IgG2b

Application: WB, FC, ELISA

Storage: 2-8°C protected from light.Do not freeze

Formulation: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Data Sheets: TDS | SDS

RECOMMENDED USAGE

Flow cytometry: The antibody MEM-267 stains immature dendritic cells that express empty cell surface MHC molecules, but not cells that express predominantly peptide loaded forms.
Western blotting: Recommended dilution: 1 µg/ml.

REFERENCES

1. Potolicchio I, et al. 2005. J Immunol 175:4935-47.
2. Carven GJ, et al. 2004. J Biol Chem 279:16561-70.

For research use only. Not intended for use in diagnostic procedures.