The mouse monoclonal antibody 7LE recognizes Lewis^a blood group antigen, a carbohydrate determinant carried on both glycolipids and glycoproteins, expressed on colonic epithelial cells. Lewis^a may be useful for detection of gastrointestinal, pancreatic and colorectal tumors.

PRODUCT DETAILS

Clone: 7LE

Specificity: Lewis A Blood Group Antigen

Reactivity: Human

Format: Purified

Isotype: Mouse IgG1

Application: IHC-P, WB, ELISA

Storage: 2-8°C protected from light.Do not freeze

Formulation: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Data Sheets: TDS | SDS

RECOMMENDED USAGE

Immunohistochemistry (paraffin sections): Recommended dilution: 5 μg/ml; positive control: colorectal adenocarcinoma; heat mediated antigen retrieval (sodium citrate); mAb incubation 1 hour / RT, detection DAB.

REFERENCES

1. Torrado J, et al. 1992. Gastroenterology 102:424-30.
2. Bara J, et al. 1988. Biochem J 254:185-93.
3. Creuzot-Garcher C, et al. 1999. Invest Ophthalmol Vis Sci 40:1631-6.

For research use only. Not intended for use in diagnostic procedures.