TDS | SDS

The OX-104 monoclonal antibody reacts with human CD200, a 40-45kD transmembrane glycoprotein that is also known as OX2. CD200 is a member of the Ig superfamily and is expressed by various cell types, including B cells, a subset of T cells, follicular dendritic cells, endothelial cells, neurons, and a subset of CD34 positive progenitor cells. The interaction between ≥ ≥ ≥ CD200 and its receptor, CD200R, is of importance in the control of macrophage and granulocyte activation and may contribute to pathways that suppress and limit their activity in a variety of tissues, suggesting a regulatory function for CD200.