PE-Cyanine7 Anti-Human CD45 (HI30)
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説明
The HI30 antibody reacts with human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others.
The HI30 antibody is widely used as a marker for human CD45 expression on T cells, B cells, monocytes, macrophages, and NK cells.
Recent Publications:
Ogata Y, Mabuchi Y, Yoshida M, Suto EG, Suzuki N, Muneta T, Sekiya I and Akazawa C. 2015. PLoS One. 10.1371/journal.pone.0129096. (Flow Cytometry)
| Name | PE-Cyanine7 Anti-Human CD45 (HI30) |
|---|---|
| Cat. No. | 60-0459 |
| Alternative Names | Leukocyte Common Antigen, LCA, Ly-5 |
| Gene ID | 5788 |
| Clone | HI30 |
| Isotype | Mouse IgG1, kappa |
| Reactivity | Human |
| Cross Reactivity | Chimpanzee |
| Format | PE-Cyanine7 |
| Application | Flow Cytometry |