Fcα/µ receptor (Fcα/µR), CD351, is a type I transmembrane protein with an Ig-like domain in extracellular portion.  It is a novel Fc receptor for IgM and IgA.  Fcα/µ receptor mRNA has been found in thymus, spleen, liver, kidney, intestines, testes, placenta, and T cell leukemia cell lines.  Fcα/µ receptor protein expression is detected on B cells, macrophages, and activated T cells.  Fcα/µ receptor mediates primary B lymphocyte endocytosis of IgM-coated Staphylococcus aureus.   It is involved in the primary stages of the immune response to microbes.

PRODUCT DETAILS

Clone: TX61

Antibody Type: Monoclonal

Reactivity: Mouse, Human

Format: PE

Host: Mouse

Isotype: IgG1, κ

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

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