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C57Bl/6 splenocytes were stained with 0.5 ug PE Anti-Mouse CD45.2 (50-0454) (solid line) or 0.5 ug PE Mouse IgG2a isotype control (dashed line).

PE Anti-Mouse CD45.2 (104)

種類 50-0454-U025
通常価格
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説明

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The 104 antibody reacts with mouse CD45.2, also known as Ly5.2, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors.

The 104 antibody is typically used as a leukocyte marker in Ly5.2 mouse strains C57BL/6, BALB/c, C58, DBA/1, DBA/2, C3H/He, CBA, 129, A and AKR. The antibody has been demonstrated to be specific for CD45.2 and is not cross-reactive with CD45.1-bearing cells.

Recent Publications:

Baba T, Yoshida T, Tanabe Y, et al. Cytoplasmic DNA accumulation preferentially triggers cell death of myeloid leukemia cells by interacting with intracellular DNA sensing pathway. Cell Death Dis. 2021 Mar 26;12(4):322. doi: 10.1038/s41419-021-03587-x. PMID: 33771977.  

» View on Nature

 

Name PE Anti-Mouse CD45.2 (104)
Cat. No. 50-0454
Alternative Names Ly5.2
Gene ID 19264
Clone 104
Isotype Mouse IgG2a, κ
Reactivity Mouse
Format PE
Application Flow Cytometry