PE anti-mouse CD262 (DR5, TRAIL-R2)
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説明
CD262, also known as DR5, TRAIL-R2, Apo-2, TRICK2, and KILLER, is a 55 kD protein. DR5 is member 10B of the TNF receptor superfamily (TNFRSF10B), widely expressed in normal tissues and some tumor cell lines. The DR5 receptor binds to TRAIL and interacts with the cytoplasmic proteins TRADD and RIP. TRAIL binding to DR5 activates NF- κB and induces apoptosis. DR5 is induced by wild-type p53.
PRODUCT DETAILS
Clone: W18111A
Antibody Type: Monoclonal
Reactivity: Mouse
Format: PE
Host: Rat
Isotype: IgG2a, λ
Applications: FC - Quality tested
Regulatory Status: RUO
Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.