CD179a, also known as VpreB, is an 18 kD member of the Ig superfamily, with an Ig V-like domain structure (that lacks the β strand of a typical V domain). CD179a associates with CD179b to form a surrogate light (SL) chain, which associates with the IgM heavy chain and the CD79a/CD79b heterodimer to form the pre-B cell receptor (PreBCR) complex. The function of CD179a/CD179b is still under investigation, though it has been reported that deficiency of CD179a and/or CD179b impairs the maturation of the B cell precursors beyond the pre-B cell stage.

PRODUCT DETAILS

Clone: R3

Antibody Type: Monoclonal

Reactivity: Mouse

Format: PE

Host: Rat

Isotype: IgG2a, κ

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

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