EPHB6 is a 110 kD protein transmembrane protein of the ephrin receptor family of tyrosine kinases, but lacks kinase activity. It is expressed on skin keratinocytes, neurons, thymocytes, immature T Cells, and a small population of peripheral CD4+ T Cells and CD8+ T Cells. Loss of EPHB6 expression has been related with increased metastatic melanoma and neuroblastoma, suggesting a role in suppressing tumorigenicity.

PRODUCT DETAILS

Clone: T49-25

Antibody Type: Monoclonal

Reactivity: Human

Format: PE

Host: Mouse

Isotype: IgG1, κ

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

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