C-type lectin domain family 1 member B (CLEC1B, CLEC2) is a 32kD, type II transmembrane protein, highly expressed on platelets and megakaryocytes. CLEC1B is involved in platelet activation and aggregation, and mediates the capture of HIV-1 by platelets. CLEC1B contains one hem-immunoreceptor tyrosine-based activation motif (hemITAM) though which interact with Syk and PLC-g. The known ligands of CLEC1B are rhodocytin and podoplanin.

PRODUCT DETAILS

Clone: AYP1

Antibody Type: Monoclonal

Reactivity: Human

Format: PE

Host: Mouse

Isotype: IgG1, κ

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

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