CD65, also referred to as ceramide-dodecasaccharide or type II fucoganglioside, is a fucosylated carbohydrate antigen which serves as a ligand for CD62E, commonly known as E-selectin. A key difference between CD65 and CD65s is that CD65 does not have a terminal sialic acid, although the rest of their structures are identical. CD65 is expressed on most myeloid cells during development, highly on granulocytes and weakly on monocytes in peripheral blood, and plays a role in cell adhesion. It has been identified as a key adhesive ligand that plays a significant role in the extravascular infiltration of cells associated with acute myeloid leukemia (AML).

PRODUCT DETAILS

Clone: VIM8

Antibody Type: Monoclonal

Reactivity: Human

Format: CD65

Host: Mouse

Isotype: IgM, κ

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.