![Human peripheral blood lymphocytes were stained with 5 uL (0.25 ug) PE Anti-Human CD23 (50-0237) (solid line) or 0.25 ug PE Mouse IgG1 isotype control (dashed line).](http://cytekbio.com/cdn/shop/products/50-0237_large.png?v=1675105827)
PE Anti-Human CD23 (EBVCS-5)
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説明
The EBVCS-5 antibody is specific for human CD23, also known as the low affinity IgE receptor (FceRII), a 45 kDa type II transmembrane protein and member of the immunoglobulin superfamily. It is expressed on most B cells and is upregulated upon activation. It is also present on mantle zone B cells, eosinophils, monocytes and a subset of T cells and platelets. CD23 plays a role in B cell development and differentiation, and also functions to regulate IgE production. Soluble secreted forms of CD23 have been reported to bind IgE, stimulate release of pro-inflammatory cytokines from monocytes, and play a role in B cell differentiation.
Name | PE Anti-Human CD23 (EBVCS-5) |
---|---|
Cat. No. | 50-0237 |
Alternative Names | FcER2, Fc?RII, Low affinity immunoglobulin epsilon Fc receptor, BLAST-2, Leu-20, B6 |
Gene ID | 2208 |
Clone | EBVCS-5 |
Isotype | Mouse IgG1, kappa |
Reactivity | Human |
Format | PE |
Application | Flow Cytometry |