CD158 molecules, also known as KIRs (killer cell immunoglobulin-like receptors), are a family of transmembrane proteins with either two (KIR2D) or three (KIR3D) Ig-like extracellular domains. Some KIRs with long cytoplasmic domains contain ITIMs and posses inhibitory functions and others with short cytoplasmic region lack ITIM and have activation functions. 15 polymorphic KIR genes have been reported in humans. CD158a is an inhibitory receptor and is mainly expressed on a subset of NK cells and a small population of CD8⁺ T cells. HP-DM1 is reported to specifically recognizes CD158a.

PRODUCT DETAILS

Clone: HP-DM1

Antibody Type: Monoclonal

Reactivity: Human

Format: PE

Host: Mouse

Isotype: IgG1, κ

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

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