The mouse monoclonal antibody HE-10 agglutinates erythrocytes of group A, and is excellent as a tumour marker in patients of blood group B and 0. It does not agglutinate erythrocytes of group B and 0. Study with specific oligosaccharides showed that the antibody HE-10 reacts with A and H antigens with chain types 3 and 4 and it does not react with A disaccharide, A trisaccharide, A type 1, A type 2, ALe^b. The antibody HE-10 does not react with normal tissue sections of donors with blood group B and 0 but it reacts specifically with malignant tissues.

PRODUCT DETAILS

Clone: HE-10

Specificity: Blood Group ABH

Reactivity: Human

Format: PE

Isotype: Mouse IgM

Application: FC

Storage: 2-8°C protected from light.Do not freeze

Formulation: Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

Data Sheets: TDS | SDS

RECOMMENDED USAGE

Flow cytometry: The suggested use of this reagent is 2-5 μg/ml. It is recommended that users titrate the antibody to obtain the optimal result for their specific application.

REFERENCES

1. Nĕmec M, et al. 1987. Vox Sang 52:125-8.
2. Vanák J, et al. 1989. Neoplasma 36:479-88.

For research use only. Not intended for use in diagnostic procedures.