Ephrin type-B receptor 4 (EphB4) is a member of the Eph family of receptor tyrosine kinases that bind to the Ephrin family of ligands. Specifically, EphB4 binds to Ephrin B2, in a process involving direct cell-to-cell interaction, to initiate signaling pathways that influence cell behavior such as differentiation, adhesion and migration. EphB4 has been shown to be involved in heart morphogenesis and angiogenesis, and in the tumorigenesis of cancers such as gliomas, breast and prostate cancer.

PRODUCT DETAILS

Clone: W20295K

Antibody Type: Monoclonal

Reactivity: Human

Format: PE

Host: Rat

Isotype: IgG2b, κ

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.