FPR1 (Formyl Peptide Receptor 1), a G protein-coupled receptor consisting of seven transmembrane domains, is expressed on phagocytic cells and other cell types such as monocytes.  FPR1 is a high affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors.  Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release.  Endogenous peptide ligands for this receptor have also been identified.   FPR1 mediates the response to invasion of the host by microbial pathogens and is important in host defense and inflammation.

PRODUCT DETAILS

Clone: W15086B

Antibody Type: Monoclonal

Reactivity: Human

Format: FITC

Host: Mouse

Isotype: IgG1, κ

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.