Fatty acids are an important source of cellular energy and serve as precursors to complex lipids such as cholesterol and membrane phospholipids. They are also essential metabolites for cell activation, proliferation and function, and can profoundly affect gene expression via nuclear receptors such as HNF4 and the PPAR family. Fatty acid uptake at the plasma membrane is controlled by CD36 (fatty acid translocase), plasma membrane-associated FABP, and Fatty Acid Transport Proteins (FATPs). The green fluorescent BODIPY C12 fatty acid can serve as a synthetic precursor in cellular metabolism. This probe can be used to measure fatty acid transport activity in many cell types by live cell imaging and flow cytometry and to screen compounds that inhibit fatty acid transport.

PRODUCT DETAILS

Clone: None

Antibody Type: None

Reactivity: Human, Mouse

Format: None

Host: None

Isotype: None

Applications: Live cell imaging - Quality tested FC - Verified In vivo imaging - Reported in the literature, not verified in house

Regulatory Status: RUO

Data Sheets: TDS | SDS

Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.