The mouse monoclonal antibody clone 11F2 binds to the human γδ T cell receptor (TCR γδ). γδ TCR is a T cell receptor consisting of two glycoprotein chains, a 45-60 kDa gamma chain and a 40-60 kDa delta chain. Unlike conventional αβ T cell receptor, which recognizes peptides bound to MHC, γδ TCR recognizes antigens in a non-MHC restricted way. TCR γδ associates with CD3 to play a role in signal transduction and is found on thymocytes and a subset of T cells. γδ T-expressing T cells are often among the first immune cells to respond to infections and can rapidly produce cytokines to initiate an immune response. Studies also suggest its role in antigen presentation and autoimmune disease.

PRODUCT DETAILS

Clone: 11F2

Specificity: TCR γ/δ

Reactivity: Human

Format: cFluor^® BYG710

Isotype: Mouse IgG1

Tested Dilution: 5 µL/Test

Application: Flow Cytometry

Storage: 2-8°C protected from light. Do not freeze

Formulation: Phosphate-buffered saline, pH 7.2, containing 0.09% sodium azide and 0.2% BSA (BSA Country of Origin USA)

Data Sheets: TDS | SDS

RECOMMENDED USAGE

Each lot of this antibody is quality control tested using flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 μL per 1 million cells in a staining volume of 100 μL. If whole blood is analyzed, then use 5 μL per 100 μL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application.

Please briefly centrifuge the reagent vial before use.

Use appropriate personal protective equipment per the product safety data sheet when using this product.

For research use only. Not intended for use in diagnostic procedures.

cFluor^® BYG710 is a tandem dye made with R-PE. Caution – Tandem dyes may show changes in their emission spectra with prolonged exposure to light or fixatives.