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C57Bl/6 bone marrow cells were stained with APC Anti-Mouse CD11b (20-0112) and 0.125 ug Biotin Anti-Mouse F4/80 Antigen (30-4801) (right panel) or 0.125 ug Biotin Rat IgG2b isotype control (left panel), followed by Streptavidin PE.

Biotin Anti-Mouse F4/80 Antigen (BM8.1)

種類 30-4801-U025
通常価格
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説明

TDS | SDS

The BM8.1 antibody is specific for mouse F4/80 antigen, a 125 kDa transmembrane protein widely expressed by members of the mononuclear phagocyte system and considered to be a key marker for mature macrophage cells. F4/80 is differentially expressed during myeloid cell development, and may be regulated by certain cytokines within the tissue microenvironment. Other cell types shown to express this antigen include Langerhans cells, Kupffer cells and dendritic cell subsets. BM8.1 is widely used together with antibodies to CD115 (c-fms), CD11b and CD11c to identify myeloid / macrophage cells by flow cytometry.

 

Recent Citations:

Brian BF 4th, Sauer ML, Greene JT, Senevirathne SE, Lindstedt AJ, Funk OL, Ruis BL, Ramirez LA, Auger JL, Swanson WL, Nunez MG, Moriarity BS, Lowell CA, Binstadt BA, Freedman TS. A dominant function of LynB kinase in preventing autoimmunity. Sci Adv. 2022 Apr 22;8(16):eabj5227. doi: 10.1126/sciadv.abj5227. Epub 2022 Apr 22. PMID: 35452291.

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Name Biotin Anti-Mouse F4/80 Antigen (BM8.1)
Cat. No. 30-4801
Alternative Names EMR1, Ly71
Gene ID 13733
Clone BM8.1
Isotype Rat IgG2b, κ
Reactivity Mouse
Format Biotin
Application Flow Cytometry