Biotin Anti-Human CD45RA (HI100)
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説明
The HI100 antibody reacts with the human CD45 isoform known as CD45RA, a protein tyrosine phosphatase of ≥ 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns. With their broad cell distribution, CD45 isoforms are critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RB, CD45RO and others.
The HI100 antibody is widely used as a marker for human CD45RA expression on naive and activated T cells, B cells, and monocytes.
| Name | Biotin Anti-Human CD45RA (HI100) |
|---|---|
| Cat. No. | 30-0458 |
| Gene ID | 5788 |
| Clone | HI100 |
| Isotype | Mouse IgG2b, kappa |
| Reactivity | Human |
| Cross Reactivity | Chimpanzee |
| Format | Biotin |
| Application | Flow Cytometry |