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C57Bl/6 splenocytes were stained with 0.125 ug APC Anti-Mouse CD45 (20-0451) (solid line) or 0.125 ug APC Rat IgG2b isotype control (dashed line).

APC Anti-Mouse CD45 (30-F11)

種類 20-0451-U025
通常価格
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説明

TDS | SDS

The 30-F11 antibody reacts with mouse CD45, which is one of the most abundant hematopoietic markers and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others.

The 30-F11 antibody is widely used as a leukocyte marker for B cells, T cell subsets and NK cell subsets.

Recent Publications:
Marsh SE, Abud EM, Lakatos A, Karimzadeh A, Yeung ST, Davtyan H, Fote GM, Lau L, Weinger JG, Lane TE, Inlay MA, Poon WW and Blurton-Jones M. 2016.Proc Natl Acad Sci USA. doi: 10.1073/pnas.1525466113. (Flow Cytometry)

Name APC Anti-Mouse CD45 (30-F11)
Cat. No. 20-0451
Alternative Names Leukocyte Common Antigen, LCA, Ly-5
Gene ID 19264
Clone 30-F11
Isotype Rat IgG2b, κ
Reactivity Mouse
Format APC
Application Flow Cytometry