CD319/CS1/CRACC/SLAMF7 (Signaling lymphocytic activation molecule family member7) is a 66 kD transmembrane protein belonging to the CD2 subset of the immunoglobulin superfamily. It is expressed on most and low or absent on monocytes and basophils.

CD319 activates immune responses in NK cells when coupled with SAP-family adaptors (SAP, EAT-2, ERT) and inhibits immune responses in the absence of SAP-family adaptors or when bound to SH-domain molecules. CD319 is a self-ligand and homophilic interaction of CD319 regulates NK cell cytolytic activity. This mouse CD319 antibody does not show cross-reactivity with rat or human.

PRODUCT DETAILS

Clone: W19300I

Antibody Type: Monoclonal

Reactivity: Mouse

Format: APC

Host: Rat

Isotype: IgG2a, κ

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

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