The Whitlow/218 linker is an 18 amino acid peptide that is widely used in chimeric antigen receptors (CAR) constructs to connect the variable heavy (VH) and variable light (VL) regions of single-chain variable fragments (scFvs).  The linker sequence was designed to increase resistance to proteolytic degradation and minimize aggregation, improving scFv stability and supporting optimal engineered cell function.

PRODUCT DETAILS

Clone: W24150D

Antibody Type: Monoclonal

Reactivity: Human, Mouse

Format: Whitlow/218 Linker

Host: Mouse

Isotype: IgG2b, κ

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.