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Alexa Fluor® 647 anti-mouse/human Bcl-6

Alexa Fluor® 647 anti-mouse/human Bcl-6

種類 648305
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説明

B-cell lymphoma 6 (Bcl-6), is an 80 kD homodimer and member of the BTB-POZ zinc finger family. It consists of one BTB (POZ) domain and six C2H2-type zinc fingers. Bcl-6 is a transcriptional repressor as well as a master regulator of germinal center reaction. On B cells, Bcl-6 induces proliferation, antibody class switching and affinity maturation, while inhibits its differentiation to plasma cells. On T cells, Bcl-6 induces its differentiation to TFH. This molecule is also expressed in some B cell lymphomas and breast cancer cells.


PRODUCT DETAILS

Clone: IG191E/A8

Antibody Type: Monoclonal

Reactivity: Human, Mouse

Format: Alexa Fluor 647

Host: Mouse

Isotype: IgG1

Applications: ICFC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS



Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.